Omegas · 8 min read
Fish oil decoded: EPA, DHA, and why the ratio matters
Most fish oil on the shelf is under-dosed. Here's what the clinical trials actually used.
EPA and DHA do different jobs
EPA (eicosapentaenoic acid) is the omega-3 most associated with cardiovascular and inflammatory benefit — it competes with arachidonic acid to produce less inflammatory eicosanoids.
DHA (docosahexaenoic acid) is structural — it makes up roughly 30% of the phospholipids in the brain's gray matter and the retina.
Clinical doses are higher than label doses
Cardiovascular trials including REDUCE-IT and VITAL used 1–4 g of combined EPA+DHA daily. Many drugstore fish oils provide just 300 mg per softgel, meaning you'd need 4–8 softgels to hit a clinically relevant dose.
ZYVORA Ultra Omega-3 delivers 1,200 mg of EPA and 800 mg of DHA per two-softgel serving in re-esterified triglyceride form — the most bioavailable molecular structure.
Purity is non-negotiable
Fish accumulate mercury, PCBs, and dioxins. Every ZYVORA batch is third-party tested to IFOS five-star purity (the highest standard in the industry) for heavy metals, oxidation (TOTOX <10), and environmental contaminants.
Citations available on request. ZYVORA articles reference peer-reviewed clinical research published in journals including JAMA, The Lancet, Nutrients, and the American Journal of Clinical Nutrition.
Citations
References available on request. ZYVORA articles cite peer-reviewed research from journals including JAMA, The Lancet, Nutrients, and the American Journal of Clinical Nutrition.
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